Introduction the past allogeneic hematopoietic cell transplantation hct is frequently complicated by acute and chronic graft versus host disease gvhd 1 2although considerable progress has been made in the development of methods to prevent or treat acute gvhd similar progress in chronic gvhd has languished by comparison after the clinical and pathologic features of this syndrome . Chronic graft versus host disease gvhd is the most common complication of allogenic bone marrow transplantation because of the protracted clinical course of chronic gvhd transplant centers and hematology oncology offices are inadequately equipped to manage these immuno incompetent patients with a multi system disorder. Chronic graft versus host disease gvhd is the most common complication of allogeneic bone marrow transplantation because of the protracted clinical course of chronic gvhd transplant centers and. When where chronic graft versus host disease might occur chronic gvhd can appear at any time after allogenic transplant or several years after your transplant chronic gvhd might occur in the skin liver eyes mouth lungs gastrointestinal tract neuromuscular system or genitourinary tract. Diagnosis and management of chronic graft versus host disease fiona l dignan12 persis amrolia3 andrew clark4 jacqueline cornish5 graham jackson6 prem mahendra7 julia j scarisbrick8 peter c taylor9 bronwen e shaw110 and michael n potter1 on behalf of the haemato oncology task force of the british committee for standards in haematology and the british society for blood and marrow
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